ITGAV - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ITGAV	ENSG00000138448	large intestine carcinoma	No drugs in record	virus receptor activity fibronectin binding protease binding voltage-gated calcium channel activity protein binding coreceptor activity metal ion binding transforming growth factor beta binding extracellular matrix binding extracellular matrix protein binding opsonin binding protein kinase C binding fibroblast growth factor binding C-X3-C chemokine binding insulin-like growth factor I binding neuregulin binding	pat-2 (C. elegans) if (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)