GIS1 - DOT1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
GIS1	YDR096W	No diseases in record	No drugs in record	metal ion binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding histone demethylase activity (H3-K36 specific) nucleic acid binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II core promoter proximal region sequence-specific DNA binding sequence-specific DNA binding DNA binding	KDM4A (H. sapiens) KDM4C (H. sapiens) KDM4B (H. sapiens)
DOT1	YDR440W	No diseases in record	No drugs in record	histone-lysine N-methyltransferase activity DNA binding histone methyltransferase activity (H3-K79 specific) nucleosomal histone binding methyltransferase activity transferase activity	DOT1L (H. sapiens)