Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
ACVR1
|
ENSG00000115170
|
DIPG
|
No drugs in record
|
protein kinase activity
protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
transforming growth factor beta receptor activity, type I
protein binding
ATP binding
peptide hormone binding
protein homodimerization activity
SMAD binding
metal ion binding
activin binding
transforming growth factor beta binding
activin receptor activity, type I
|
sax (D. melanogaster)
|
KRAS
|
ENSG00000133703
|
pancreatic
colorectal
lung
thyroid
AML
other tumour types
|
No drugs in record
|
GTPase activity
protein binding
GTP binding
GMP binding
GDP binding
LRR domain binding
protein complex binding
|
RAS1 (S. cerevisiae)
RAS2 (S. cerevisiae)
let-60 (C. elegans)
Ras85D (D. melanogaster)
|