KRAS - PTCH1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KRAS	ENSG00000133703	pancreatic colorectal lung thyroid AML other tumour types	No drugs in record	GTPase activity protein binding GTP binding GMP binding GDP binding LRR domain binding protein complex binding	RAS1 (S. cerevisiae) RAS2 (S. cerevisiae) let-60 (C. elegans) Ras85D (D. melanogaster)
PTCH1	ENSG00000185920	skin basal cell medulloblastoma	No drugs in record	patched binding smoothened binding protein binding hedgehog receptor activity heparin binding cholesterol binding cyclin binding protein complex binding hedgehog family protein binding	NCR1 (S. cerevisiae) ptc-1 (C. elegans) ptc-3 (C. elegans) ptc-2 (C. elegans) ptc (D. melanogaster)