KRAS - TCF7L2

H. sapiens

SSL interaction

 PCNA TCF7L2 AKT1 ABL1 COPS5 CUL1 BRCA1 EP300 SUMO2 EGFR SRC FBXW7 CDKN1A RB1 KRAS UBC CSNK2A1 ESR1 MYC MAP3K7 HDAC1 TP53 CTNNB1 SKP1 AR CREBBP SKP2 SUMO1 RAF1 A2M ABCB5 ACSM4 ACTR2 ACVRL1 ADAM22 ADAMTSL5 ADCY8 ALKBH3 ALKBH7 ANAPC1 ANAPC4 ANXA5 ARID1B ARL4A ARPC2 ARPC3 ASB16 BCORL1 BFSP1 BRIX1 C11orf72 C12orf56 C6 C6orf48 C9orf84 CA12 CACNA2D2 CALR

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
KRAS ENSG00000133703 pancreatic
colorectal
lung
thyroid
AML
other tumour types

No drugs in record

GTPase activity
protein binding
GTP binding
GMP binding
GDP binding
LRR domain binding
protein complex binding
RAS1 (S. cerevisiae)
RAS2 (S. cerevisiae)
let-60 (C. elegans)
Ras85D (D. melanogaster)
TCF7L2 ENSG00000148737 colorectal

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II repressing transcription factor binding
transcription factor activity, sequence-specific DNA binding
protein binding
beta-catenin binding
transcription factor binding
protein kinase binding
nuclear hormone receptor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
gamma-catenin binding
armadillo repeat domain binding
pop-1 (C. elegans)
pan (D. melanogaster)