KRAS - TCF7L2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KRAS	ENSG00000133703	pancreatic colorectal lung thyroid AML other tumour types	No drugs in record	GTPase activity protein binding GTP binding GMP binding GDP binding LRR domain binding protein complex binding	RAS1 (S. cerevisiae) RAS2 (S. cerevisiae) let-60 (C. elegans) Ras85D (D. melanogaster)
TCF7L2	ENSG00000148737	colorectal	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II repressing transcription factor binding transcription factor activity, sequence-specific DNA binding protein binding beta-catenin binding transcription factor binding protein kinase binding nuclear hormone receptor binding sequence-specific DNA binding transcription regulatory region DNA binding gamma-catenin binding armadillo repeat domain binding	pop-1 (C. elegans) pan (D. melanogaster)