KDM5B - KRAS

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KDM5B	ENSG00000117139	No diseases in record	No drugs in record	DNA binding transcription factor activity, sequence-specific DNA binding transcription corepressor activity protein binding zinc ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors histone demethylase activity histone demethylase activity (H3-K4 specific) histone demethylase activity (H3-trimethyl-K4 specific) histone demethylase activity (H3-dimethyl-K4 specific)	JHD2 (S. cerevisiae) rbr-2 (C. elegans) Jarid2 (D. melanogaster)
KRAS	ENSG00000133703	pancreatic colorectal lung thyroid AML other tumour types	No drugs in record	GTPase activity protein binding GTP binding GMP binding GDP binding LRR domain binding protein complex binding	RAS1 (S. cerevisiae) RAS2 (S. cerevisiae) let-60 (C. elegans) Ras85D (D. melanogaster)