OCRL - KRAS

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
OCRL	ENSG00000122126	No diseases in record	No drugs in record	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity GTPase activator activity protein binding Rac GTPase binding inositol-1,4,5-trisphosphate 5-phosphatase activity inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity inositol phosphate phosphatase activity phosphatidylinositol bisphosphate phosphatase activity	INP51 (S. cerevisiae) INP52 (S. cerevisiae) INP53 (S. cerevisiae)
KRAS	ENSG00000133703	pancreatic colorectal lung thyroid AML other tumour types	No drugs in record	GTPase activity protein binding GTP binding GMP binding GDP binding LRR domain binding protein complex binding	RAS1 (S. cerevisiae) RAS2 (S. cerevisiae) let-60 (C. elegans) Ras85D (D. melanogaster)