RB1 - TGFBR2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RB1	ENSG00000139687	retinoblastoma sarcoma breast small cell lung carcinoma	No drugs in record	core promoter binding RNA polymerase II activating transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding kinase binding ubiquitin protein ligase binding identical protein binding androgen receptor binding phosphoprotein binding	lin-35 (C. elegans) Rbf2 (D. melanogaster)
TGFBR2	ENSG00000163513	head and neck colorectal	No drugs in record	transmembrane receptor protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity transforming growth factor beta-activated receptor activity transforming growth factor beta receptor activity, type II protein binding ATP binding glycosaminoglycan binding mitogen-activated protein kinase kinase kinase binding type I transforming growth factor beta receptor binding SMAD binding metal ion binding transforming growth factor beta binding	No GO terms in record