PML - POLE

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PML	ENSG00000140464	APL ALL	No drugs in record	DNA binding protein binding zinc ion binding ubiquitin protein ligase binding SUMO binding protein homodimerization activity SMAD binding	No GO terms in record
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)