KDM5A - SRC

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KDM5A	ENSG00000073614	AML	No drugs in record	DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding zinc ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors chromatin DNA binding histone demethylase activity	JHD2 (S. cerevisiae) rbr-2 (C. elegans)
SRC	ENSG00000197122	colorectal cancer endometrial carcinoma	BOSUTINIB DASATINIB VANDETANIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity SH3/SH2 adaptor activity protein kinase C binding receptor binding insulin receptor binding integrin binding protein binding ATP binding protein C-terminus binding kinase activity enzyme binding kinase binding heme binding estrogen receptor binding SH2 domain binding ion channel binding ephrin receptor binding phosphoprotein binding hormone receptor binding growth factor receptor binding scaffold protein binding cadherin binding involved in cell-cell adhesion	Src64B (D. melanogaster)