Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
KDM5A
|
ENSG00000073614
|
AML
|
No drugs in record
|
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
zinc ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
chromatin DNA binding
histone demethylase activity
|
JHD2 (S. cerevisiae)
rbr-2 (C. elegans)
|
SRC
|
ENSG00000197122
|
colorectal cancer
endometrial carcinoma
|
BOSUTINIB
DASATINIB
VANDETANIB
|
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
SH3/SH2 adaptor activity
protein kinase C binding
receptor binding
insulin receptor binding
integrin binding
protein binding
ATP binding
protein C-terminus binding
kinase activity
enzyme binding
kinase binding
heme binding
estrogen receptor binding
SH2 domain binding
ion channel binding
ephrin receptor binding
phosphoprotein binding
hormone receptor binding
growth factor receptor binding
scaffold protein binding
cadherin binding involved in cell-cell adhesion
|
Src64B (D. melanogaster)
|