AGO1 - AGO2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
AGO1	ENSG00000092847	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core binding core promoter binding RNA binding double-stranded RNA binding single-stranded RNA binding protein binding miRNA binding endoribonuclease activity enzyme binding endoribonuclease activity, producing 5'-phosphomonoesters	alg-1 (C. elegans) alg-2 (C. elegans) AGO1 (D. melanogaster)
AGO2	ENSG00000123908	No diseases in record	No drugs in record	RNA 7-methylguanosine cap binding RNA polymerase II core binding core promoter binding double-stranded RNA binding single-stranded RNA binding mRNA binding translation initiation factor activity endoribonuclease activity protein binding protein C-terminus binding bidentate ribonuclease III activity siRNA binding miRNA binding metal ion binding endoribonuclease activity, cleaving siRNA-paired mRNA endoribonuclease activity, cleaving miRNA-paired mRNA mRNA cap binding	alg-1 (C. elegans) alg-2 (C. elegans) AGO1 (D. melanogaster)