ETV6 - RB1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ETV6 ENSG00000139083 congenital fibrosarcoma
multiple different leukaemia and lymphoma tumour types including ALL
secretory breast
MDS

No drugs in record

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein domain specific binding
aop (D. melanogaster)
RB1 ENSG00000139687 retinoblastoma
sarcoma
breast
small cell lung carcinoma

No drugs in record

core promoter binding
RNA polymerase II activating transcription factor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
kinase binding
ubiquitin protein ligase binding
identical protein binding
androgen receptor binding
phosphoprotein binding
lin-35 (C. elegans)
Rbf2 (D. melanogaster)