FGFR1 - CALR

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FGFR1	ENSG00000077782	MPN NHL salivary adenoma	LENVATINIB NINTEDANIB PAZOPANIB PONATINIB REGORAFENIB	protein tyrosine kinase activity fibroblast growth factor-activated receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding heparin binding 1-phosphatidylinositol-3-kinase activity fibroblast growth factor binding identical protein binding protein homodimerization activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity	egl-15 (C. elegans) htl (D. melanogaster)
CALR	ENSG00000179218	MPN MDS	No drugs in record	complement component C1q binding glycoprotein binding DNA binding mRNA binding integrin binding iron ion binding calcium ion binding protein binding zinc ion binding carbohydrate binding ubiquitin protein ligase binding peptide binding hormone binding protein binding involved in protein folding androgen receptor binding unfolded protein binding chaperone binding	CNE1 (S. cerevisiae) crt-1 (C. elegans)