E2F1 - NRG1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
E2F1	ENSG00000101412	No diseases in record	No drugs in record	core promoter binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding protein kinase binding sequence-specific DNA binding protein dimerization activity RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II regulatory region DNA binding	E2f1 (D. melanogaster)
NRG1	ENSG00000157168	NSCLC	No drugs in record	transcription cofactor activity protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity cytokine activity ErbB-2 class receptor binding integrin binding growth factor activity transmembrane receptor protein tyrosine kinase activator activity receptor tyrosine kinase binding ErbB-3 class receptor binding chemorepellent activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II transcription factor binding DNA binding sequence-specific DNA binding metal ion binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II repressing transcription factor binding nucleic acid binding	No GO terms in record