GSK3B - SMAD6

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
GSK3B	ENSG00000082701	No diseases in record	LITHIUM CARBONATE LITHIUM CITRATE	RNA polymerase II transcription factor binding p53 binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding beta-catenin binding kinase activity protein kinase binding ubiquitin protein ligase binding protein kinase A catalytic subunit binding tau-protein kinase activity NF-kappaB binding	MRK1 (S. cerevisiae) RIM11 (S. cerevisiae) gsk-3 (C. elegans) sgg (D. melanogaster) gskt (D. melanogaster)
SMAD6	ENSG00000137834	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity ubiquitin protein ligase binding type I transforming growth factor beta receptor binding identical protein binding transcription regulatory region DNA binding metal ion binding co-SMAD binding I-SMAD binding R-SMAD binding type I activin receptor binding	daf-14 (C. elegans) daf-8 (C. elegans) Dad (D. melanogaster)