CREBBP - IDH2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CREBBP	ENSG00000005339	ALL AML DLBCL B-NHL	No drugs in record	core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription factor binding RNA polymerase II activating transcription factor binding RNA polymerase II transcription coactivator activity transcriptional repressor activity, RNA polymerase II transcription factor binding p53 binding chromatin binding damaged DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity histone acetyltransferase activity signal transducer activity protein binding transcription factor binding zinc ion binding acetyltransferase activity peptide N-acetyltransferase activity MRF binding	BDF1 (S. cerevisiae) BDF2 (S. cerevisiae) nej (D. melanogaster)
IDH2	ENSG00000182054	glioblastoma	No drugs in record	magnesium ion binding isocitrate dehydrogenase (NADP+) activity NAD binding isocitrate dehydrogenase (NAD+) activity catalytic activity metal ion binding oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor RNA binding	IDP1 (S. cerevisiae) IDP2 (S. cerevisiae) IDP3 (S. cerevisiae)