ACVR1 - TP53

H. sapiens

SDL interaction


Gene Name Gene ID Diseases Drugs GO terms Orthologs
ACVR1 ENSG00000115170 DIPG

No drugs in record

protein kinase activity
protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
transforming growth factor beta receptor activity, type I
protein binding
ATP binding
peptide hormone binding
protein homodimerization activity
SMAD binding
metal ion binding
activin binding
transforming growth factor beta binding
activin receptor activity, type I
sax (D. melanogaster)
TP53 ENSG00000141510 breast
Spitzoid tumour
multiple other tumour types
adrenocortical carcinoma

No drugs in record

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protease binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
copper ion binding
protein binding
ATP binding
transcription factor binding
zinc ion binding
enzyme binding
protein kinase binding
protein phosphatase binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
histone acetyltransferase binding
identical protein binding
sequence-specific DNA binding
protein self-association
transcription regulatory region DNA binding
protein heterodimerization activity
protein N-terminus binding
chaperone binding
protein phosphatase 2A binding

No GO terms in record