ACVR1 - SRC

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ACVR1	ENSG00000115170	DIPG	No drugs in record	protein kinase activity protein serine/threonine kinase activity transmembrane receptor protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity transforming growth factor beta receptor activity, type I protein binding ATP binding peptide hormone binding protein homodimerization activity SMAD binding metal ion binding activin binding transforming growth factor beta binding activin receptor activity, type I	sax (D. melanogaster)
SRC	ENSG00000197122	colorectal cancer endometrial carcinoma	BOSUTINIB DASATINIB VANDETANIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity SH3/SH2 adaptor activity protein kinase C binding receptor binding insulin receptor binding integrin binding protein binding ATP binding protein C-terminus binding kinase activity enzyme binding kinase binding heme binding estrogen receptor binding SH2 domain binding ion channel binding ephrin receptor binding phosphoprotein binding hormone receptor binding growth factor receptor binding scaffold protein binding cadherin binding involved in cell-cell adhesion	Src64B (D. melanogaster)