NSD1 - SIN3A

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NSD1	ENSG00000165671	AML	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding chromatin binding transcription cofactor activity transcription corepressor activity zinc ion binding histone-lysine N-methyltransferase activity estrogen receptor binding histone methyltransferase activity (H4-K20 specific) retinoic acid receptor binding retinoid X receptor binding thyroid hormone receptor binding histone methyltransferase activity (H3-K36 specific) androgen receptor binding	SET2 (S. cerevisiae)
SIN3A	ENSG00000169375	No diseases in record	No drugs in record	transcription regulatory region sequence-specific DNA binding RNA polymerase II activating transcription factor binding RNA polymerase II repressing transcription factor binding RNA polymerase II transcription corepressor activity chromatin binding transcription factor activity, sequence-specific DNA binding RNA binding protein binding protein complex binding protein deacetylase activity histone deacetylase activity transcription cofactor activity protein heterodimerization activity	SIN3 (S. cerevisiae) sin-3 (C. elegans) Sin3A (D. melanogaster)