MED12 - HSF1

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MED12	ENSG00000184634	uterine leiomyoma fibroadenoma phyllodes tumour	No drugs in record	RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription cofactor activity RNA polymerase II transcription coactivator activity chromatin binding transcription cofactor activity transcription coactivator activity receptor activity protein binding beta-catenin binding protein C-terminus binding protein domain specific binding ligand-dependent nuclear receptor transcription coactivator activity vitamin D receptor binding thyroid hormone receptor binding ubiquitin protein ligase activity	dpy-22 (C. elegans) kto (D. melanogaster)
HSF1	ENSG00000185122	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding protein kinase binding heat shock protein binding identical protein binding STAT family protein binding sequence-specific single stranded DNA binding promoter-specific chromatin binding sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	HSF1 (S. cerevisiae) hsf-1 (C. elegans)