PLCG1 - NRG1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PLCG1	ENSG00000124181	angiosarcoma	No drugs in record	phosphatidylinositol phospholipase C activity phospholipase C activity signal transducer activity, downstream of receptor neurotrophin TRKA receptor binding calcium ion binding protein binding protein kinase binding receptor tyrosine kinase binding glutamate receptor binding	PLC1 (S. cerevisiae) plc-3 (C. elegans) sl (D. melanogaster)
NRG1	ENSG00000157168	NSCLC	No drugs in record	transcription cofactor activity protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity cytokine activity ErbB-2 class receptor binding integrin binding growth factor activity transmembrane receptor protein tyrosine kinase activator activity receptor tyrosine kinase binding ErbB-3 class receptor binding chemorepellent activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II transcription factor binding DNA binding sequence-specific DNA binding metal ion binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II repressing transcription factor binding nucleic acid binding	No GO terms in record