IRS4 - JUN

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
IRS4	ENSG00000133124	glioma rhabdomyosarcoma melanoma breast cancer T-ALL	No drugs in record	signal transducer activity SH3/SH2 adaptor activity insulin receptor binding protein binding phosphatidylinositol 3-kinase binding molecular_function	chico (D. melanogaster)
JUN	ENSG00000177606	sarcoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II activating transcription factor binding transcriptional activator activity, RNA polymerase II transcription factor binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding transcription coactivator activity GTPase activator activity protein binding transcription factor binding enzyme binding cAMP response element binding identical protein binding protein homodimerization activity transcription regulatory region DNA binding protein heterodimerization activity R-SMAD binding HMG box domain binding	Jra (D. melanogaster)