XIAP - POLE

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
XIAP	ENSG00000101966	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding zinc ion binding ligase activity identical protein binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process ubiquitin protein ligase activity	Diap2 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)