GATA1 - ERBB4

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
GATA1	ENSG00000102145	megakaryoblastic leukaemia of Downs syndrome	No drugs in record	transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding core promoter binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription factor binding enhancer sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding p53 binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding zinc ion binding DNA binding, bending chromatin DNA binding sequence-specific DNA binding C2H2 zinc finger domain binding	DAL80 (S. cerevisiae) GLN3 (S. cerevisiae) GZF3 (S. cerevisiae)
ERBB4	ENSG00000178568	melanoma gastric NSCLC	AFATINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding protein binding ATP binding protein homodimerization activity transcription regulatory region DNA binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	let-23 (C. elegans) Egfr (D. melanogaster)