TRIM28 - NSD1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TRIM28	ENSG00000130726	No diseases in record	No drugs in record	RNA polymerase II transcription coactivator activity DNA binding chromatin binding transcription corepressor activity protein kinase activity ubiquitin-protein transferase activity protein binding zinc ion binding ligase activity ubiquitin protein ligase binding Krueppel-associated box domain binding chromo shadow domain binding promoter-specific chromatin binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding	bon (D. melanogaster)
NSD1	ENSG00000165671	AML	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding chromatin binding transcription cofactor activity transcription corepressor activity zinc ion binding histone-lysine N-methyltransferase activity estrogen receptor binding histone methyltransferase activity (H4-K20 specific) retinoic acid receptor binding retinoid X receptor binding thyroid hormone receptor binding histone methyltransferase activity (H3-K36 specific) androgen receptor binding	SET2 (S. cerevisiae)