SH2B1 - PTPN11

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
SH2B1 ENSG00000178188

No diseases in record

No drugs in record

signal transducer activity
protein binding
signaling adaptor activity

No GO terms in record

PTPN11 ENSG00000179295 JMML
AML
MDS

No drugs in record

phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
SH3/SH2 adaptor activity
insulin receptor binding
protein binding
1-phosphatidylinositol-3-kinase activity
protein domain specific binding
receptor tyrosine kinase binding
D1 dopamine receptor binding
phospholipase binding
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
cell adhesion molecule binding
peptide hormone receptor binding
PTP1 (S. cerevisiae)
ptp-2 (C. elegans)
csw (D. melanogaster)