RPS3 - POLE

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RPS3	ENSG00000149273	No diseases in record	No drugs in record	DNA binding damaged DNA binding RNA binding mRNA binding structural constituent of ribosome DNA-(apurinic or apyrimidinic site) lyase activity endodeoxyribonuclease activity protein binding microtubule binding transcription factor binding tubulin binding enzyme binding kinase binding protein kinase binding Hsp70 protein binding SUMO binding oxidized purine DNA binding oxidized pyrimidine DNA binding ubiquitin-like protein conjugating enzyme binding protein kinase A binding iron-sulfur cluster binding Hsp90 protein binding small ribosomal subunit rRNA binding supercoiled DNA binding DNA N-glycosylase activity oxidized purine nucleobase lesion DNA N-glycosylase activity	RPS3 (S. cerevisiae) rps-3 (C. elegans) RpS3 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)