SMAD7 - EZH2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMAD7	ENSG00000101665	No diseases in record	No drugs in record	transcription factor activity, sequence-specific DNA binding protein binding collagen binding beta-catenin binding transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity ubiquitin protein ligase binding type I transforming growth factor beta receptor binding transcription regulatory region DNA binding metal ion binding activin binding I-SMAD binding	daf-14 (C. elegans) daf-8 (C. elegans) Dad (D. melanogaster)
EZH2	ENSG00000106462	DLBCL	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding core promoter binding DNA binding chromatin binding protein binding protein-lysine N-methyltransferase activity histone-lysine N-methyltransferase activity chromatin DNA binding histone methyltransferase activity ribonucleoprotein complex binding histone methyltransferase activity (H3-K27 specific) primary miRNA binding promoter-specific chromatin binding	SET2 (S. cerevisiae) lin-59 (C. elegans) E(z) (D. melanogaster)