FURIN - PTPN11

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FURIN	ENSG00000140564	No diseases in record	No drugs in record	protease binding endopeptidase activity serine-type endopeptidase activity serine-type endopeptidase inhibitor activity protein binding peptidase activity peptide binding metal ion binding nerve growth factor binding	KEX2 (S. cerevisiae) Fur2 (D. melanogaster)
PTPN11	ENSG00000179295	JMML AML MDS	No drugs in record	phosphoprotein phosphatase activity protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity SH3/SH2 adaptor activity insulin receptor binding protein binding 1-phosphatidylinositol-3-kinase activity protein domain specific binding receptor tyrosine kinase binding D1 dopamine receptor binding phospholipase binding insulin receptor substrate binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity cell adhesion molecule binding peptide hormone receptor binding	PTP1 (S. cerevisiae) ptp-2 (C. elegans) csw (D. melanogaster)