PSEN1 - CALR

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PSEN1	ENSG00000080815	No diseases in record	No drugs in record	endopeptidase activity aspartic-type endopeptidase activity calcium channel activity protein binding beta-catenin binding PDZ domain binding cadherin binding	sel-12 (C. elegans)
CALR	ENSG00000179218	MPN MDS	No drugs in record	complement component C1q binding glycoprotein binding DNA binding mRNA binding integrin binding iron ion binding calcium ion binding protein binding zinc ion binding carbohydrate binding ubiquitin protein ligase binding peptide binding hormone binding protein binding involved in protein folding androgen receptor binding unfolded protein binding chaperone binding	CNE1 (S. cerevisiae) crt-1 (C. elegans)