GMPS - SMAD3

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
GMPS ENSG00000163655 AML

No drugs in record

GMP synthase activity
GMP synthase (glutamine-hydrolyzing) activity
ATP binding
pyrophosphatase activity
GUA1 (S. cerevisiae)
gmps-1 (C. elegans)
bur (D. melanogaster)
SMAD3 ENSG00000166949 colorectal carcinoma
oral squamous cell carcinoma

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
core promoter proximal region sequence-specific DNA binding
RNA polymerase II activating transcription factor binding
transcription factor activity, sequence-specific DNA binding
transforming growth factor beta receptor binding
protein binding
collagen binding
beta-catenin binding
transcription factor binding
zinc ion binding
protein kinase binding
phosphatase binding
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
chromatin DNA binding
ubiquitin protein ligase binding
enhancer binding
identical protein binding
protein homodimerization activity
ubiquitin binding
bHLH transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
co-SMAD binding
R-SMAD binding
transcription factor activity, protein binding
sma-3 (C. elegans)
sma-2 (C. elegans)