CCND1 - POLE

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CCND1	ENSG00000110092	CLL B-ALL breast	PALBOCICLIB	transcription corepressor activity protein kinase activity protein binding transcription factor binding cyclin-dependent protein serine/threonine kinase regulator activity enzyme binding protein kinase binding protein complex binding histone deacetylase binding proline-rich region binding	cyd-1 (C. elegans) CycD (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)