MLH1 - SOS1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MLH1	ENSG00000076242	colorectal endometrial ovarian CNS tumours CNS	No drugs in record	chromatin binding protein binding ATP binding ATPase activity guanine/thymine mispair binding single-stranded DNA binding MutSalpha complex binding mismatched DNA binding heteroduplex DNA loop binding DNA insertion or deletion binding dinucleotide insertion or deletion binding double-stranded DNA binding DNA binding	MLH1 (S. cerevisiae) Mlh1 (D. melanogaster)
SOS1	ENSG00000115904	No diseases in record	No drugs in record	DNA binding guanyl-nucleotide exchange factor activity Ras guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding SH3 domain binding protein heterodimerization activity	CDC25 (S. cerevisiae) Sos (D. melanogaster)