EP300 - IGF1R

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
EP300 ENSG00000100393 colorectal
breast
pancreatic
AML
ALL
DLBCL

No drugs in record

RNA polymerase II core promoter sequence-specific DNA binding
core promoter binding
RNA polymerase II activating transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
transcription coactivator activity
histone acetyltransferase activity
lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
protein binding
beta-catenin binding
protein C-terminus binding
transcription factor binding
zinc ion binding
acetyltransferase activity
transferase activity, transferring acyl groups
chromatin DNA binding
activating transcription factor binding
peptide N-acetyltransferase activity
nuclear hormone receptor binding
androgen receptor binding
pre-mRNA intronic binding
BDF1 (S. cerevisiae)
BDF2 (S. cerevisiae)
nej (D. melanogaster)
IGF1R ENSG00000140443

No diseases in record

MECASERMIN
MECASERMIN RINFABATE
protein tyrosine kinase activity
insulin-like growth factor-activated receptor activity
insulin receptor binding
protein binding
insulin-like growth factor binding
ATP binding
insulin-like growth factor I binding
identical protein binding
phosphatidylinositol 3-kinase binding
insulin binding
insulin receptor substrate binding
daf-2 (C. elegans)