RARA - NRG1

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RARA	ENSG00000131759	APL	ACITRETIN ADAPALENE ALITRETINOIN ETRETINATE ISOTRETINOIN TAZAROTENE TRETINOIN	translation repressor activity, nucleic acid binding RNA polymerase II regulatory region sequence-specific DNA binding retinoic acid binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity retinoic acid receptor activity transcription coactivator activity transcription corepressor activity receptor binding protein binding transcription factor binding drug binding zinc ion binding enzyme binding protein domain specific binding chromatin DNA binding histone deacetylase binding protein kinase B binding retinoic acid-responsive element binding protein heterodimerization activity mRNA 5'-UTR binding protein kinase A binding alpha-actinin binding	EcR (D. melanogaster)
NRG1	ENSG00000157168	NSCLC	No drugs in record	transcription cofactor activity protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity cytokine activity ErbB-2 class receptor binding integrin binding growth factor activity transmembrane receptor protein tyrosine kinase activator activity receptor tyrosine kinase binding ErbB-3 class receptor binding chemorepellent activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II transcription factor binding DNA binding sequence-specific DNA binding metal ion binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II repressing transcription factor binding nucleic acid binding	No GO terms in record