NPM1 - SP1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NPM1	ENSG00000181163	NHL APL AML	No drugs in record	transcription coactivator activity RNA binding protein kinase inhibitor activity protein binding protein kinase binding Tat protein binding histone binding protein homodimerization activity ribosomal large subunit binding ribosomal small subunit binding protein heterodimerization activity NF-kappaB binding unfolded protein binding	No GO terms in record
SP1	ENSG00000185591	No diseases in record	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding core promoter sequence-specific DNA binding RNA polymerase II repressing transcription factor binding DNA binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding protein binding protein C-terminus binding transcription factor binding histone acetyltransferase binding protein homodimerization activity histone deacetylase binding bHLH transcription factor binding sequence-specific DNA binding transcription regulatory region DNA binding metal ion binding HMG box domain binding RNA polymerase II transcription factor activity, sequence-specific DNA binding	No GO terms in record