IDH2 - SP1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
IDH2	ENSG00000182054	glioblastoma	No drugs in record	magnesium ion binding isocitrate dehydrogenase (NADP+) activity NAD binding isocitrate dehydrogenase (NAD+) activity catalytic activity metal ion binding oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor RNA binding	IDP1 (S. cerevisiae) IDP2 (S. cerevisiae) IDP3 (S. cerevisiae)
SP1	ENSG00000185591	No diseases in record	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding core promoter sequence-specific DNA binding RNA polymerase II repressing transcription factor binding DNA binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding protein binding protein C-terminus binding transcription factor binding histone acetyltransferase binding protein homodimerization activity histone deacetylase binding bHLH transcription factor binding sequence-specific DNA binding transcription regulatory region DNA binding metal ion binding HMG box domain binding RNA polymerase II transcription factor activity, sequence-specific DNA binding	No GO terms in record