SPTBN1 - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SPTBN1	ENSG00000115306	No diseases in record	No drugs in record	actin binding Ras guanyl-nucleotide exchange factor activity structural constituent of cytoskeleton protein binding calmodulin binding phospholipid binding ankyrin binding protein complex binding GTPase binding cadherin binding involved in cell-cell adhesion	No GO terms in record
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)