GRIA4 - PTPN11

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
GRIA4	ENSG00000152578	No diseases in record	PERAMPANEL TOPIRAMATE	ionotropic glutamate receptor activity AMPA glutamate receptor activity excitatory extracellular ligand-gated ion channel activity extracellular-glutamate-gated ion channel activity	glr-1 (C. elegans)
PTPN11	ENSG00000179295	JMML AML MDS	No drugs in record	phosphoprotein phosphatase activity protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity SH3/SH2 adaptor activity insulin receptor binding protein binding 1-phosphatidylinositol-3-kinase activity protein domain specific binding receptor tyrosine kinase binding D1 dopamine receptor binding phospholipase binding insulin receptor substrate binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity cell adhesion molecule binding peptide hormone receptor binding	PTP1 (S. cerevisiae) ptp-2 (C. elegans) csw (D. melanogaster)