ABL1 - TAL1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ABL1	ENSG00000097007	CML ALL T-ALL	BOSUTINIB DASATINIB IMATINIB NILOTINIB PONATINIB REGORAFENIB	magnesium ion binding DNA binding actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding protein binding ATP binding protein C-terminus binding SH3 domain binding syntaxin binding manganese ion binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding receptor binding	abl-1 (C. elegans) Abl (D. melanogaster)
TAL1	ENSG00000162367	lymphoblastic leukaemia/biphasic	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding enzyme binding histone deacetylase binding transcription regulatory region DNA binding protein heterodimerization activity E-box binding sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity transferase activity catalytic activity	HLH3B (D. melanogaster)