ABL1 - BCOR

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ABL1 ENSG00000097007 CML
ALL
T-ALL
BOSUTINIB
DASATINIB
IMATINIB
NILOTINIB
PONATINIB
REGORAFENIB
magnesium ion binding
DNA binding
actin monomer binding
nicotinate-nucleotide adenylyltransferase activity
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
SH3 domain binding
syntaxin binding
manganese ion binding
actin filament binding
mitogen-activated protein kinase binding
proline-rich region binding
receptor binding
abl-1 (C. elegans)
Abl (D. melanogaster)
BCOR ENSG00000183337 retinoblastoma
AML
APL

No drugs in record

transcription corepressor activity
protein binding
transcription factor binding
heat shock protein binding
histone deacetylase binding
transcription regulatory region DNA binding
ubiquitin-protein transferase activity
HOS4 (S. cerevisiae)