ABL1 - LIG4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ABL1	ENSG00000097007	CML ALL T-ALL	BOSUTINIB DASATINIB IMATINIB NILOTINIB PONATINIB REGORAFENIB	magnesium ion binding DNA binding actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding protein binding ATP binding protein C-terminus binding SH3 domain binding syntaxin binding manganese ion binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding receptor binding	abl-1 (C. elegans) Abl (D. melanogaster)
LIG4	ENSG00000174405	No diseases in record	No drugs in record	DNA binding DNA ligase activity DNA ligase (ATP) activity protein binding ATP binding protein C-terminus binding ligase activity metal ion binding	DNL4 (S. cerevisiae) lig-4 (C. elegans) Lig4 (D. melanogaster)