ERBB2 - KCNH1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ERBB2	ENSG00000141736	breast ovarian other tumour types NSCLC gastric	AFATINIB LAPATINIB PERTUZUMAB TRASTUZUMAB TRASTUZUMAB EMTANSINE VANDETANIB	RNA polymerase I core binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding protein C-terminus binding protein phosphatase binding identical protein binding ErbB-3 class receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity protein dimerization activity growth factor binding	let-23 (C. elegans) Egfr (D. melanogaster)
KCNH1	ENSG00000143473	No diseases in record	DALFAMPRIDINE DOFETILIDE GUANIDINE	phosphorelay sensor kinase activity delayed rectifier potassium channel activity protein binding calmodulin binding protein kinase binding identical protein binding ion channel binding protein heterodimerization activity 14-3-3 protein binding phosphatidylinositol bisphosphate binding cyclic nucleotide binding	eag (D. melanogaster)