XPO1 - ERCC3

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
XPO1	ENSG00000082898	CLL	No drugs in record	RNA binding nuclear export signal receptor activity transporter activity nucleocytoplasmic transporter activity protein binding Ran GTPase binding protein domain specific binding	CRM1 (S. cerevisiae) xpo-1 (C. elegans) emb (D. melanogaster)
ERCC3	ENSG00000163161	skin basal cell skin squamous cell melanoma	No drugs in record	DNA binding damaged DNA binding ATP-dependent DNA helicase activity helicase activity protein binding ATP binding GTP binding protein C-terminus binding transcription factor binding ATPase activity dATP binding peptide binding 3'-5' DNA helicase activity protein N-terminus binding protein kinase activity DNA-dependent ATPase activity RNA polymerase II carboxy-terminal domain kinase activity	SSL2 (S. cerevisiae) xpb-1 (C. elegans) hay (D. melanogaster)