CBL - SREBF2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CBL	ENSG00000110395	AML JMML MDS	No drugs in record	phosphotyrosine residue binding transcription factor activity, sequence-specific DNA binding ubiquitin-protein transferase activity signal transducer activity calcium ion binding protein binding zinc ion binding ligase activity SH3 domain binding receptor tyrosine kinase binding phosphatidylinositol 3-kinase regulatory subunit binding ephrin receptor binding ubiquitin protein ligase activity cadherin binding involved in cell-cell adhesion	sli-1 (C. elegans) Cbl (D. melanogaster)
SREBF2	ENSG00000198911	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding protein binding protein C-terminus binding protein dimerization activity E-box binding C-8 sterol isomerase activity	sbp-1 (C. elegans)