ARAF - CBL

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ARAF	ENSG00000078061	cholangiocarcinoma lung adenocarcinoma Langerhans cell histiocytosis	No drugs in record	protein kinase activity protein serine/threonine kinase activity signal transducer activity, downstream of receptor protein binding ATP binding metal ion binding	lin-45 (C. elegans)
CBL	ENSG00000110395	AML JMML MDS	No drugs in record	phosphotyrosine residue binding transcription factor activity, sequence-specific DNA binding ubiquitin-protein transferase activity signal transducer activity calcium ion binding protein binding zinc ion binding ligase activity SH3 domain binding receptor tyrosine kinase binding phosphatidylinositol 3-kinase regulatory subunit binding ephrin receptor binding ubiquitin protein ligase activity cadherin binding involved in cell-cell adhesion	sli-1 (C. elegans) Cbl (D. melanogaster)