APC - SMAD6

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
APC ENSG00000134982 colorectal
pancreatic
desmoid
hepatoblastoma
glioma
other CNS

No drugs in record

protein binding
beta-catenin binding
microtubule binding
protein kinase regulator activity
protein kinase binding
gamma-catenin binding
microtubule plus-end binding
cadherin binding
apr-1 (C. elegans)
Apc2 (D. melanogaster)
Apc (D. melanogaster)
SMAD6 ENSG00000137834

No diseases in record

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
ubiquitin protein ligase binding
type I transforming growth factor beta receptor binding
identical protein binding
transcription regulatory region DNA binding
metal ion binding
co-SMAD binding
I-SMAD binding
R-SMAD binding
type I activin receptor binding
daf-14 (C. elegans)
daf-8 (C. elegans)
Dad (D. melanogaster)