APC - TCF7L2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
APC	ENSG00000134982	colorectal pancreatic desmoid hepatoblastoma glioma other CNS	No drugs in record	protein binding beta-catenin binding microtubule binding protein kinase regulator activity protein kinase binding gamma-catenin binding microtubule plus-end binding cadherin binding	apr-1 (C. elegans) Apc2 (D. melanogaster) Apc (D. melanogaster)
TCF7L2	ENSG00000148737	colorectal	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II repressing transcription factor binding transcription factor activity, sequence-specific DNA binding protein binding beta-catenin binding transcription factor binding protein kinase binding nuclear hormone receptor binding sequence-specific DNA binding transcription regulatory region DNA binding gamma-catenin binding armadillo repeat domain binding	pop-1 (C. elegans) pan (D. melanogaster)