MPL - JAK1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MPL	ENSG00000117400	MPN	ELTROMBOPAG ROMIPLOSTIM	transmembrane signaling receptor activity protein binding thrombopoietin receptor activity	No GO terms in record
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)