GATA1 - JAK1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
GATA1 ENSG00000102145 megakaryoblastic leukaemia of Downs syndrome

No drugs in record

transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
p53 binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
DNA binding, bending
chromatin DNA binding
sequence-specific DNA binding
C2H2 zinc finger domain binding
DAL80 (S. cerevisiae)
GLN3 (S. cerevisiae)
GZF3 (S. cerevisiae)
JAK1 ENSG00000162434 ALL
RUXOLITINIB
TOFACITINIB
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
growth hormone receptor binding
protein binding
ATP binding
protein phosphatase binding
ubiquitin protein ligase binding
CCR5 chemokine receptor binding
metal ion binding
hop (D. melanogaster)